Bitter gourd melon poisoning belongs to the category of plant poisoning, the specific treatment has the following four steps: first, thorough gastric lavage, each time the introduction of gastric lavage fluid amount of 30-50 ml, subdivided doses, 10-20 times, the overall introduction of gastric lavage fluid amount of 8,000-10,000 ml or so, with warm boiled water as the gastric lavage fluid is the most appropriate. If the patient is awake, gastric lavage can be done by inducing vomiting. If the patient is comatose and unconscious, it is necessary to intubate with a gastric lavage machine and perform electro-mechanical gastric lavage until colorless, clarified and tasteless gastric fluid is induced, at which time gastric lavage is completed. Secondly, high level enema such as mannitol and magnesium sulfate can be performed to excrete the toxins that have been absorbed into the intestinal lumen by means of diarrhea. Third, detoxification drugs can be applied to remove the toxin components that have been absorbed into the bloodstream. Since there is no symptomatic detoxification drug for bitter gourd melon, general detoxification drugs, such as injectable vitamin C, can be used for detoxification. Fourthly, in hospitals where conditions permit, blood purification treatment is also feasible, such as continuous hemofiltration or hemoperfusion are treatments that can be taken.