Zhi Bai Di Huang Wan and Zuo Gui Wan both have the effect of nourishing kidney yin, while Zhi Bai Di Huang Wan has the effect of clearing heat and lowering fire, which should be used in clinical diagnosis, and it is recommended to use the medication under the guidance of a professional physician. Zuo Gui Wan contains Radix Rehmanniae Praeparata, Semen Cuscutae, and Radix Achyranthis Bidentatae, which are nourishing kidney yin. It is used in cases of kidney yin insufficiency, including lumbar soreness and knee weakness, tinnitus, spermatorrhea, mental fatigue, dryness of tongue and mouth, and night sweating (sweating abnormally after falling asleep, but stopping after waking up). Attention, pregnant women should not take, children are prohibited, adverse reactions are not clear. Zhi Bai Di Huang Wan contains Zhi Mu, Huang Bai, Shu Di Huang, etc., not only has the effect of nourishing kidney yin, but also has the effect of clearing heat and lowering fire, in addition to treating common kidney yin deficiency, can also be used to improve the dry mouth and sore throat, hand and foot, heart and heat, heartburn, insomnia and other symptoms of deficiency and exuberance of fire. Adverse effects and contraindications are not known.