Hyperbaric oxygen chamber in the regular operation of the general no side effects, if the operation is not appropriate may produce oxygen toxicity, decompression sickness, decompression complications, middle ear pneumatic pressure injury, lung pneumatic pressure injury and other adverse reactions, but not limited to five. 1. Oxygen toxicity: prolonged inhalation of high concentrations of oxygen will lead to functional damage to the body, manifested as chest pain, cough, dizziness, dyspnea, etc.. 2. Decompression sickness: generally appear in the operator decompression too fast, resulting in excessive decompression, gas dissolved in the tissue or blood, serious cases can lead to gas embolism. Patients may also experience complications such as red and swollen joints, itchy skin, nausea and vomiting. 3. Middle ear pneumatic pressure injury: in the process of hyperbaric oxygen boosting, the external pressure increases, the gas can not enter the tympanic chamber through the Eustachian tube, the pressure difference between inside and outside occurs, causing congestion and edema of the tympanic mucosa. 4. Lung pneumatic pressure injury: it means that pneumothorax is not found or treated in time, and chest gas expansion occurs during decompression, causing pressure on the lungs. In addition, there can also be sinus pneumatic pressure injury, nosebleeds and other manifestations, but overall the hyperbaric chamber as long as the regular operation is still relatively safe, it is recommended that the treatment under the guidance of the doctor.