The main clinical manifestations of degenerative arthritis of the knee in the elderly are joint pain, joint pressure, joint swelling, joint stiffness, joint deformity, friction sensation, joint instability and restricted movement. Age-related degeneration is the main cause of degenerative arthritis in the elderly. After middle and old age, all tissues and organs undergo degenerative changes, and bone and joint tissues are no exception; degenerative changes, especially in weight-bearing joints and joints with a lot of movement, tend to occur. Excessive weight-bearing or overuse of certain joints can promote the development of degenerative changes. The main damage of degenerative changes in the elderly is in the cartilage of the joints, which degenerates, softens, loses elasticity, fractures, and falls off. Endochondral ossification forms bone fragments at the edges of the joint, known as “bone spurs”. As the central cartilage of the joint is worn to the maximum or even disappears, the cartilage at the periphery of the joint may also become thickened and hyperplastic, causing narrowing and unevenness of the joint cavity and deformation of the bone ends. This can also result in limited motion and joint deformity. Treatment of degenerative (osteophytic) osteoarthritis of the knee in the elderly mainly includes: (a) Conservative treatment 1. Sometimes non-pharmacological treatment alone can help patients improve their current quality of life. Raise patients’ awareness of risk factors and promote a healthy lifestyle. Exercises such as walking and swimming are beneficial not only for mild to moderate elderly patients with degenerative arthritis of the knee, but also for severe patients. Physiotherapy is suitable for the chronic phase of osteoarthritis of the knee and is effective in relieving pain in the subacute phase. It also increases local blood circulation and makes the synovial inflammation subside so that synovial fluid secretion is normal, metabolic waste of cartilage is easily discharged, cartilage is fully nourished and the degeneration of cartilage is delayed. Physical therapy includes electrotherapy, magnetic therapy, vinegar therapy, wax therapy, hydrotherapy and visible light therapy, etc. 3, acupuncture and massage using the immune and analgesic effects of acupuncture, through reasonable acupuncture points and correct acupuncture treatment of osteoarthritis of the knee, can relieve symptoms and prevent further deterioration. 4, drug therapy Western medicine drug therapy is currently the most commonly used method of treatment 0A, in recent years the progress is faster, but also achieved better results. The commonly used clinical drugs are painkillers and non-steroidal anti-inflammatory drugs (NSAIDs). NSAIDs can be used when patients are ineffective to analgesics. However, NSAIDs cause a wide range of adverse reactions, with gastrointestinal reactions leading the list. In addition, there is also some damage to the liver, cardiovascular, nervous system, hematopoietic system, and skin. Selective inhibitors and specific inhibitors of COX-2, the inducible enzyme of cyclooxygenase (COX), can significantly reduce gastrointestinal adverse reactions and thus have a good gastrointestinal safety. For example, meloxicam (Meloxican), rofecoxib (Rofecoxib), celecoxib (celecoxib), etc. As a centrally acting oral analgesic tramadol (Tramadol), a synthetic opioid antagonist, can be used in patients with moderate to severe pain as an adjunctive treatment when NSAIDs do not adequately control symptoms. Chinese medicine internal use Chinese medicine considers knee oA to be in the category of bone paralysis and tendon paralysis, which is a deficiency of the liver and kidney as the root, wind, cold, dampness, phlegm and stasis paralysis of the meridians, and loss of nourishment of the tendons and bones as the standard. Clinical treatment is often based on tonifying the kidney and strengthening the bones, activating blood circulation and removing blood stasis, warming the meridians and dispersing cold, etc., and good results have been achieved. Local medication Western medicine often uses topical topical application such as Furtalin latex, Fenbid gel and Umax cream, Federal analgesic cream cream. Chinese medicine practitioners mostly use Chinese herbal soup, cream and powder to fumigate and apply to the affected area, so that they can continue to act directly on the affected area. The fumigation, compressing and ionizing method of Chinese medicine can obviously improve local microcirculation, reduce intraosseous pressure and eliminate synovial inflammation. The Chinese medicine used has the functions of regulating qi, activating blood circulation, warming menstruation, dispersing cold, dispelling wind and dampness, and strengthening tendons and bones. Intra-articular administration Intra-articular injection of sodium hyaluronate can supplement the deficiency of endogenous hyaluronic acid; protect joint tissues and eliminate pain-causing substances; improve joint mobility; inhibit the precipitation of proteoglycans from the cartilage matrix; and provide feedback to the biosynthesis of its own polymeric hyaluronic acid. Intra-articular injection of sodium hyaluronate has been clinically proven to be effective in early stage patients with severe pain but no obvious deformity, but it is less effective in patients with large amount of exudate and significant obesity, and the long-term efficacy is uncertain. (2) Surgery is to reduce pain, improve joint function, correct deformity and poor alignment, reduce vertical load and shear force, eliminate intra-articular causes of joint surface erosion, and when the disease is clearly progressive and is an indication for surgery, artificial joint replacement can be considered to establish a new joint. 1, arthroscopy and microscopic surgery: Arthroscopy is a minimally invasive technique developed in the last two decades, providing a new method for the diagnosis and treatment of chronic arthritis, and a large number of clinical results show that it is superior to traditional arthrocentesis in terms of efficacy and complications. (1) Arthroscopic irrigation: By removing intra-articular debris, proteolytic products, collagenase, matrix enzymes, inflammatory mediators, and calcified pyrophosphate crystals, the symptoms can be relieved. (2) Joint cleaning: flushing to remove hypertrophic synovial membrane, bony flab, free body and fibrocartilage, restoration of worn joint surface into rows, meniscal trimming, and adhesion release. (3) Cartilage planing and shaping: planing to stimulate regeneration and repair of femoral condyle fibrocartilage. (2) Total artificial knee surface replacement: total knee surface replacement is the gold standard for the treatment of end-stage knee diseases including knee osteoarthritis.