Bone and soft tissue tumors are very rare, leading to frequent misdiagnosis and inappropriate treatment by patients and doctors. Even specialists from famous tertiary hospitals without basic training in bone tumor can not avoid inappropriate treatment. It is recommended that patients who find bone and soft tissue tumors should seek medical consultation from specialists. Only a few hospitals in China have established independent bone and soft tissue tumor centers, and most of the orthopedic or surgical specialists in hospitals are very famous in other specialties, but when dealing with bone and soft tissue tumors, they cannot follow the diagnosis and treatment routine of tumors because they do not understand them. When bone and soft tissue tumor patients visit the hospital, we need to know the following contents: 1. medical history and general condition 2. previous tumor history and family history 3. patient’s clinical examination 4. various imaging examinations, which may cost a lot and seem unnecessary to patients or non-oncology specialists, but are very important to bone tumor patients, and are important information for doctors to understand various objective manifestations of the most primitive lesions, once after Once improper treatment, it is impossible to restore the lesion, especially when it is diagnosed as benign tumor and postoperative as malignant tumor, causing irreversible loss to patients. 5. Biopsy of lesions is the only step to make a clear diagnosis before surgery, and is the key to get a correct diagnosis. The correct diagnosis of bone and soft tissue tumors requires the cooperation of experts in clinical, imaging and pathology. The difference between benign and malignant clinicopathological diagnosis can bring limb disfigurement and even life-threatening consequences to patients. In conclusion, patients should visit bone and soft tissue tumor specialists; non-specialist doctors should treat bone and soft tissue tumors with caution.