Liver protection tablets and entecavir can be taken about two hours intermittently, and the specific conditions are in accordance with the doctor’s instructions. 1. Liver protection tablets: it is a Chinese patent medicine, with the indications of dredging the liver and regulating qi, strengthening the spleen and eliminating food. It has the effect of lowering transaminase and is used for chronic hepatitis and early cirrhosis. Adverse reactions, occasionally nausea, abdominal discomfort. During the period of taking medicine, liver function should be tested regularly, and cold and greasy food should be prohibited. 2. Entecavir: The purpose is to inhibit viral replication. It is suitable for the treatment of chronic adult hepatitis B with active viral replication, persistent elevation of serum alanine aminotransferase or active lesions in liver histology. The most common adverse reactions include headache, fatigue, vertigo and nausea, immune system disorders, adverse reactions in the skin and subcutaneous tissues, metabolic and nutritional disorders, and elevated transaminases. Pregnant and lactating women, children, elderly use of drugs need to be under the strict guidance of a physician, pay attention to the choice of drug dosage, and monitor renal function. All of the above medications should be used under the guidance of a doctor, avoid self-medication, so as not to delay the condition, if there is any discomfort in the process of taking medication, immediately consult a doctor.