There is no definite value for how long ankylosing spondylitis patients can live, but the disease itself will not directly affect the patients’ life expectancy. Ankylosing spondylitis is an autoimmune disease that mainly affects the central axis of the skeleton, the large joints of the limbs and the spine, and can lead to joint deformities, ankylosis and even disability in severe cases, but the disease itself does not have a direct impact on the patient’s own life expectancy, so there is no clear value on how long ankylosing spondylitis patients can live. Ankylosing spondylitis can lead to childbirth difficulties for women, or serious fractures of the spine, or anemia, impaired renal function, interstitial fibrosis, etc. When the disease is not well controlled, ankylosing spondylitis may indirectly affect the patient’s life expectancy, so the patient needs to actively cooperate with the appropriate treatment after diagnosis in order to avoid this kind of problem. It is recommended that patients diagnosed with ankylosing spondylitis go to the rheumatology and immunology department of a regular hospital and receive standardized treatment under the guidance of a doctor to avoid delays in their condition, as well as regular follow-ups.