Abdomen refers to the stomach, femur refers to the thighs, and groin is the shallow groove formed at the very bottom where the stomach joins the thighs. Pain over the groin may be caused by acute appendicitis, inguinal hernia, enlarged inguinal lymph nodes and so on. 1. Acute appendicitis: usually caused by structural abnormalities of the appendix, obstruction of the appendiceal lumen, bacterial infection, etc. The patient will have pain in the right side of the abdomen above the groin, which may also be accompanied by nausea, vomiting and other symptoms. 2. Inguinal hernia: Congenital anatomical abnormalities in the inguinal region or acquired weakness in the abdominal position cause the abdominal contents to protrude outward, which leads to the appearance of inguinal hernia. When the hernia sac becomes incarcerated, abdominal pain over the inguinal area will occur. 3. Enlargement of inguinal lymph nodes: mostly caused by infection, leukemia, lymphoma and other tumors, patients may have symptoms of abdominal pain above the groin, accompanied by fever, headache, fatigue and other manifestations. In addition, ulcerative colitis, inflammation of the reproductive organs can also lead to pain above the groin, it is recommended to go to the hospital in time, after clarifying the cause of the disease, under the guidance of the doctor to carry out the appropriate treatment and therapy.