According to the condition to determine the isolation management and treatment places, light cases can be isolated centrally and symptomatic supportive treatment; ordinary, heavy and critical cases should be treated centrally in designated hospitals. 1. General treatment: patients should rest in bed, ensure sufficient energy and nutritional intake; closely observe vital signs, such as oxygen saturation; according to the condition, test laboratory indicators, such as blood routine, CRP, arterial blood gas analysis, etc.; also can be given standardized and effective oxygen therapy measures; avoid blindly applying antibacterial drugs. 2. Antiviral therapy: the current antiviral means are ritonavir tablets, ambavizumab, COVID-19 human immunoglobulin, recovery plasma of recovered patients, and so on. 3. Immunotherapy: mainly glucocorticoids, interleukin 6 inhibitors. 4. Anticoagulation therapy: low molecular heparin or ordinary heparin can be used if the disease progresses quickly and there is no contraindication. 5. Prone position therapy: it is suitable for ordinary, severe and critical patients with high risk factors for severe disease and rapid disease progression, and is recommended to be used for not less than 12 hours a day. 6. Psychological intervention: psychological counseling of patients should be strengthened, supplemented by medication if necessary. 7. Traditional Chinese medicine treatment: such as Lianhua Qingdian capsule can be used to assist the treatment.