Erythromycin Isotretinoin Gel is usually used for about 7 days to see the effect, but the specific time to see the effect is related to the individual’s physical condition and the severity of acne. Erythromycin Isotretinoin Gel is mainly used for the local treatment of mild and moderate acne vulgaris, and has a better effect on both inflammatory and non-inflammatory lesions, and the specific time of effect is related to the patient’s physique and the severity of the condition. Erythromycin Isotretinoin Gel can regulate epithelial cell growth and differentiation, inhibit the activity of sebaceous glands, reduce sebum secretion, inhibit Propionibacterium acnes and reduce inflammation. Some patients may experience discomfort such as tingling, burning and irritation during use, erythema and peeling at the site of application, which should be temporarily discontinued, and is prohibited for those who are allergic to any of the ingredients in the drug. It is recommended that patients under the guidance of a doctor, strictly follow the instructions of the doctor to use the drug, not blindly use the drug or change the dose of the drug without authorization, so as not to cause adverse effects on the body.