Aging is a natural law and facial rejuvenation is the reverse process of aging. A young face has a continuation of fat distribution within and during each aesthetic unit of the face, making it look balanced and homogeneous. The key to maintaining a youthful, rounded face with smooth lines is 1. the support of effective bone tissue volume; 2. the proper ratio of skin, subcutaneous tissue (mainly fat) thickness and muscle strength. This also makes the young face appear three distinct arcs: (1) the forehead arc formed by the skin that protrudes from the surface of the frontal bone downward and dives into the upper lid crease; (2) the midface arc that extends from the lower lid to the mandible and supports the forward expansion of the cheek; (3) and the jawline that links the two sides of the mastoid process. The skin and muscles of a gradually aging face do not change very much, while the lack of subcutaneous adipose tissue volume makes the frontal, brow and mid-facial prominence disappear, and the skin is relatively excessive and shifted in a certain direction by muscle pulling and gravity, resulting in frequent deviations in various parts of the face. Either there is too much fat or too little fat, showing a “valley”-like topography, with areas like peaks indicating too much fat and areas like valleys indicating fat atrophy. This unbalanced and discontinuous distribution of fat is one of the main culprits for the loss of roundness and regularity of facial contours. To achieve facial rejuvenation, it is necessary to remove the surplus and make up for the deficiency. Cosmetic injections mainly use a syringe as a tool to achieve facial rejuvenation and beauty by injecting materials or drugs of biological origin or synthetic ones. At present, the two mainstream materials of filler injections are hyaluronic acid injection and autologous fat transplantation, both of which can be used to remove wrinkles and fillers, so what is the difference between the two and how should we choose? I. Nature and function Autologous fat facial transplantation: Suck out excess fat from your own waist, abdomen, thighs and other parts, and after proper treatment, fill in the face with multi-point multi-level injection through refined injection technology, compared with traditional open facelift, autologous fat transplantation facial modification is safer, less traumatic, no scarring, no foreign body, less pain. Fat grafting solves the main problem of soft tissue volume. Fat rebalancing of the facial area combined with facial microfat aspiration technology are good facial rejuvenation treatments, especially for candidates who are a little older, have serious soft tissue volume loss and require full facial fillers. Fat tissue volume is mainly maintained by adipocytes, which are mainly composed of triglycerides, and therefore their hardness and support are weaker than hyaluronic acid. When the aging of the face is dominated by the reduction of skeletal support capacity, and skin laxity is not serious, in this case, we can consider supplementing the important support points of the face such as the arch of the eyebrows, the bridge of the nose, the temples, the chin, and the bony projections of the zygomatic prominence with relatively hard filling material (hyaluronic acid), which can change the forward convexity of these parts and thus achieve the overall lifting of the face. Hyaluronic acid is a polymeric polysaccharide widely found in the extracellular matrix of nodal tissues in the human body, which plays an important physiological function of water retention, maintenance of extracellular space, regulation of osmotic pressure, lubrication and promotion of cell repair. Nowadays, there are many domestic and foreign brands of hyaluronic acid approved to be listed, and there are various products with similar publicity effects and basically the same indications for filling, so that doctors and beauty lovers are at a loss to choose. Generally speaking, the higher the degree of cross-linking, the larger the molecular particles, and the higher the concentration of HA, the greater the elasticity coefficient (G,) and the stronger the colloidal hardness, the less likely it is to be displaced, and the slower its absorption, and of course, the greater its injection resistance. Therefore products that tend to have this property are very suitable for deep dermal, subcutaneous, supraperiosteal and other deep fillers, which can be used for shaping facial contours and eliminating deeper static wrinkles. For example, it can be used to correct depressions such as cheeks and temporal areas, as well as for forehead augmentation, chin augmentation and mildly low nose contouring, and for filling nasolabial folds. At the same time, the harder and more viscous hyaluronic acid is also one of the effective means to achieve support reconstruction. Hyaluronic acid filling in the periosteal plane can effectively improve the anterior convexity of key support areas, and the increased anterior convexity can effectively antagonize the downward movement of soft tissues and achieve overall facial lifting. Conversely, the smaller the degree of cross-linking, the lower the concentration of HA and the smaller the molecular particles, the weaker its colloidal hardness and the faster it will be absorbed, so it will be suitable for superficial injections to eliminate superficial wrinkles and help skin retain and lock water, and no palpable or visible nodules will appear after injection. For example, the main component of what we often call hydration injection is actually non-cross-linked, low concentration, small molecule hyaluronic acid. Second, the operation time Hyaluronic acid injection is easy to operate and can generally be completed within 30 minutes, with immediate results. Autologous fat filling, on the other hand, first requires the use of swelling liquid fat suction technology to suck out excess fat from the waist, abdomen, thighs and other parts of the body, and then after centrifugation, purification, purification and some special treatment, the processed fat is injected into the designated parts, and the whole process takes about 2 hours. Third, the effect maintenance The molecular size of hyaluronic acid, the degree of cross-linking, concentration, etc. together affect the maintenance time of its effect, generally ranging from 6-12 months, more than this time need to be injected again to maintain the effect. The effect maintenance of autologous fat filler is related to the survival rate of fat cells. The survival rate of fat transplantation varies from individual to individual, generally ranging from 30% to 90%. The survived fat is consistent with the original fat in the transplanted area, so the effect is maintained for a long time or even permanently. If you are too worried about the uncertainty of the survival rate of fat grafting, you may also consider the option of SVF-gel, a new type of tissue rich in svf cells and extracellular matrix, which is physically extracted from adipose tissue and is more stable than fat grafting and has a much higher survival rate than fat grafting. grafting, typically no less than 85%. (For more information about SVF-gel, please click here.) IV. Post-operative recovery Hyaluronic acid injection can be completed within 30 minutes, and the recovery period is short. Because of the retention rate of fat, autologous fat transplantation is generally over-injected, plus the stress reaction caused by surgical trauma, there will be 2-4 weeks of post-operative swelling, as the stress reaction subsides and fat absorption, post-operative swelling will gradually dissipate. 3-6 months after complete stability, it is a cocoon into a butterfly, replaced by a full, delicate, young face. After fat filling, not only is the face younger, it is simply full of vitality. 5. Surgical risks Whether it is hyaluronic acid injection or fat grafting, it must be confirmed that there are no contraindications to treatment before surgery. Both fat grafting and hyaluronic acid have the risk of vascular embolism, but hyaluronic acid can be saved by using hyaluronic acid lysing enzyme in case of clogging of blood vessels or unsatisfactory results. And autologous fat filler requires high requirements for doctors and environment, more sessions than hyaluronic acid injection, and more technical content. Whether it is hyaluronic acid injection or autologous fat injection, please keep in mind that you must choose a regular medical institution and a doctor who is familiar with the anatomical levels of the face and the location of blood vessels! Stay away from black clinics and be responsible for yourself VI. Summary Hyaluronic acid of different nature has different applications, so it is very good for filling both fine facial wrinkles and partial folds, such as fine wrinkles between the eyebrows, periorbital area, periorbital area, etc., and also very effective for deep static wrinkles, and can also be used for local contour shaping and facial lifting of the face, plus its quick and convenient operation and short-term postoperative recovery, so it is very suitable for It is also very effective for deep static wrinkles and facial contouring and face lifting. In the case of serious soft tissue loss, we recommend autologous fat transplantation, especially for full face fillers. The surgical operation, post-operative recovery and surgical risks are more complicated than hyaluronic acid injection, so customers should ensure sufficient time and wait patiently for post-operative recovery. Full facial fat transplantation sometimes requires hyaluronic acid filler to improve the support of the face to achieve more beautiful and natural results.