The sequelae of Guillain-Barre syndrome generally include motor impairment, sensory impairment, and functional impairment of urination and defecation. Motor disorders include such as quadriplegia, paraplegia, and paraplegia generally refers to the paralysis of both lower limbs. If there is tetraplegia or paraplegia, we must be careful and pay attention to the following points in bed: 1. Be careful of pressure sores: how to avoid pressure sores, the first turn over, the second to ensure protein intake; 2. Lower limb thrombosis, generally refers to deep vein thrombosis, especially to be careful of intermuscular vein thrombosis, because intermuscular vein thrombosis does not have any symptoms. Do passive exercises of the lower limbs, especially ankle exercises; 3, bedridden, be careful of the occurrence of pneumonia, pneumonia prevention is to turn and pat the back, if there is voluntary sputum function, let him cough, if not can help to do breathing training, such as abdominal breathing, inhalation to let the stomach bulge, out of breath, generally with shrinking lips breathing, mouth to shrink up out of breath, this is helpful. Sensory disorders generally include temperature and pain sensory disorders. From the rehabilitation point of view, we can use hot and cold stimulation to see if it can help him. From the rehabilitation point of view, there is a kind of intermittent clean catheterization, which may be helpful. If intermittent clean catheterization does not help, only indwelling catheterization can be used, but indwelling catheterization must prevent retrograde infection, urinary tract infection affecting the kidneys.