To determine whether cosmetic allergy can be applied to the face, neck and other cosmetics, the reference symptoms are as follows: 1, the emergence of clearly defined edematous erythema, which can be seen on the corn to soybean-sized papules, papules, blisters, some of the rashes fused into a piece, scratching can appear vesicles, oozing. Scratching is too obvious, the hands are not clean to cause localized suppurative infection, and there can be pus scabs; 2, the more serious cases can appear in the cosmetic application site of the whole red and swollen, and in the lips and other mucous membrane parts of the swelling; 3, systemic infections with more serious symptoms can appear fever, the highest can be more than 38.5 ℃.