The common causes of swollen flesh next to the big teeth in the mouth are inflammation of the wisdom teeth, periodontal abscess, periapical periodontitis, etc., the causes of different treatments are different, and should be consulted in time, the common treatments are general treatment, medication, surgery and so on. 1. Inflammation of wisdom teeth: mild inflammation of wisdom teeth can be prescribed antibacterial drugs to control inflammation, such as metronidazole and amoxicillin. Peri-crown rinsing is also needed. Peri-coronary rinsing is to remove the plaque, food debris, etc., if there is an abscess in the peri-coronary area, it is also necessary to incise and drain the pus. 2. Periodontal abscess: it is an acute confined purulent inflammation that occurs in the wall of the periodontal pocket, usually occurs in the deep periodontal pocket of severe periodontitis, and is caused by infection. Pay attention to drink more water, do not eat spicy food, need to carry out systematic periodontal treatment and follow the doctor’s instructions to take amoxicillin, metronidazole and other drugs for treatment, if necessary, also need to take surgical treatment. 3. Periapical abscess: generally caused by infection of the pulp, generally the pulp cavity of the pulp tissue has been completely necrotic, oozing and may have pus phenomenon. The flesh next to the tooth is swollen. This time need to take root canal treatment, after the operation under the guidance of the doctor to take anti-inflammatory drugs, such as cefdinir, amoxicillin and so on. The presence of swollen flesh next to a large tooth in the mouth, it is necessary to consult a doctor in time to avoid delaying the condition.