Testicular pain by pinching with hands may be normal, or it may be caused by testicular inflammation, trauma, testicular or adnexal torsion, which needs to be treated with medication or surgery as prescribed by the doctor. 1. Normal situation: under normal circumstances, pinching the testicles with the hand may cause pain, which needs no special treatment, just don’t pinch. 2. testicular inflammation: testicular pinch pain may be caused by testicular inflammation and other reasons, with the doctor’s guidance to use anti-inflammatory drugs, such as amoxicillin, etc., but also to change the bad habits, avoid touching the testicles with your hands, at the same time pay attention to the local hygiene, wear loose and breathable underwear. 3. Trauma: testicular pinch pain may also be caused by trauma to the testicular area. Patients can apply cold compresses appropriately according to their own conditions, and when the pain symptoms are obvious, they can take ibuprofen, acetaminophen and other medications to relieve them. 4. Testicular or adnexal torsion: Testicular or adnexal torsion can lead to testicular pinching pain, or even severe pain in the scrotum, which can be relieved by using scrotal support as prescribed by the doctor. Testicular torsion carries a risk of testicular necrosis and requires emergency scrotal incision and exploration. Testicular pinching pain may also be caused by other reasons, it is recommended to go to the hospital as soon as possible to do a checkup to clarify the cause of timely treatment.