Back of hand pain is considered to be caused by multiple peripheral neuritis, tenosynovitis, rheumatoid arthritis or trauma. 1. Multiple peripheral neuritis: Multiple peripheral neuritis may be caused by drugs, nutritional disorders, chemicals, infections, immunity and other factors. Sensory disturbances may occur, such as pins and needles, ants, and tenderness on the back of the hand, accompanied by pale skin, coldness, and excessive sweating. 2. Tenosynovitis: Tenosynovitis is caused by chronic strain, trauma, rheumatic fever and other factors. Symptoms such as localized pain, pressure pain, limited joint movement, etc., partly accompanied by radiating pain, manifested as pain on the back of the hand. 3. Rheumatoid arthritis: Rheumatoid arthritis may be caused by autoimmune, genetic, smoking, infection and other factors. Joint swelling, morning stiffness, pain and other symptoms can occur, which can be manifested as pain in the back of the hand, and some of the severe symptoms can also appear in the case of joint deformity. 4. Trauma: the back of the hand pain also need to consider trauma caused by the back of the hand tendons and other soft tissue injury or fracture, and accompanied by localized swelling and activity restrictions and other symptoms. There are many other causes of hand and back pain, such as cervical spondylosis, gout, etc., if the persistence of unrelieved, it is recommended to go to the hospital in a timely manner, relevant examinations, so as to clarify the cause of the disease, and comply with the doctor’s instructions for targeted treatment, so as to avoid delaying the condition.