Because of the stress caused by bad mood, depression, the first should be adjusted for the source of stress, the ordinary way is to strengthen physical exercise, enhance social activities, divert attention to achieve a balanced state of work and rest nutrition. If after removing stress factors still have low mood, for new people or things are lack of interest and other symptoms, it is necessary to seek medical advice to exclude whether there is depression and other diseases. 1, strengthen physical exercise: exercise can stimulate the secretion of dopamine and endorphins in the body, these two neurotransmitters can mainly cause pleasant emotions, so you can strengthen the way to change the mood and release stress by strengthening exercise. 2, enhance social activities: talking with people can often distract and reduce the negative effects of work stress. Also confide in friends can be in comfort to reverse the mood and improve the mood. In addition, the gathering to eat delicious food will also promote the secretion of dopamine, thus gaining happiness; 3, increase outdoor activities: use holiday time or spare time, go out for a walk, in the surrounding environment in a good place to take a break from activities can relax and relieve stress. At the same time, look at the beautiful natural environment can also enhance the love of life, to prevent depression; 4, empty thoughts: you can listen to music, watch variety shows or look at art exhibitions or shopping comic book shows when you are alone, appropriate emptying, meditation, to avoid too many thoughts too mixed instead of distress. If it is too much stress caused by bad mood, depression, you can try to relieve the pressure through the above methods, if possible to change the lifestyle or work environment. If the symptoms are still serious through self-regulation, you can use medication or combine with psychotherapy. You can choose medication such as escitalopram, fluvoxamine, sertraline, venlafaxine, duloxetine and so on, usually pay attention to more rest, to ensure that there is sufficient sleep time, in the work of the combination of work and rest.