After sleeping on the arm pressure especially painful, considering that the patient’s long time compression of the elbow led to the arm ischemia and hypoxia or brachial plexus nerve injury, first of all, should remove the compression, if a short rest can not be relieved, it should be timely to the regular hospital for medical treatment. Sleeping with the arm if the head pressure on the arm for too long, will lead to localized ischemia and hypoxia of the arm, which will appear numbness and mild pain. Usually, the arm can return to normal within a few minutes after removing the pressure, and the patient can also give the arm massage and hot compresses. If you wake up from sleep with a lot of pain in your arm that doesn’t go away after resting, or if you have movement problems in your arm, then consider brachial plexus injury. Brachial plexus nerve injury is mild, you can use vitamin B1 and other nutritive drugs, with physical therapy, massage treatment. If the damage to the brachial plexus is more serious, surgery may be needed. The above drugs should be used under the guidance of a doctor, avoid self-medication.