Pacemaker therapy, also known as deep brain electrical stimulation (DBS), can control the motor symptoms of Parkinson’s disease, such as tremor, rigidity, and bradykinesia; reduce the duration and severity of agitation, reduce the fluctuation of symptoms, and delay the opening period; reduce the dosage of levodopa drugs in patients with Parkinson’s disease for a long time, which is effective in the control of motor symptoms for a long time and can improve the quality of life. quality of life and improve the patient’s ability to perform daily life. Many people are concerned about the surgical trauma of pacemaker therapy for Parkinson’s disease and do not know enough about the procedure. Pacemaker therapy consists of surgical implantation of a pacemaker device and post-operative program control. The procedure consists of the installation of a stereotactic head frame on the patient’s head under local anesthesia, MRI scanning, image transfer to the surgical planning system to calculate the coordinates of the target, electrophysiological signal recording during surgery to further determine the location of the target, stimulation electrode implantation into the target, temporary electrical stimulation to observe the improvement of limb movement, temporary electrical stimulation to prove the accuracy of the electrode implantation, and finally implantation and connection of the pulse generator. The procedure is completed. About 1 month after the operation, after the patient’s brain condition has recovered and stabilized, the pulse generator will be turned on by the remote control of the in vitro programmable instrument and the stimulation parameters will be set to achieve a satisfactory treatment effect. If the condition progresses or changes, the stimulation parameters can be adjusted remotely outside the body to regain a satisfactory outcome. Pacemaker surgery is a minimally invasive procedure with minimal damage to the human body; at the same time, the surgical positioning system is used to develop the surgical plan, ensuring accurate target locations and safe electrode implantation paths. Moreover, brain pacemaker treatment for Parkinson’s disease is reversible and adjustable, which can effectively improve the quality of life of patients. It is understood that the current suitable surgical treatment is for primary tremor and tremor symptoms of Parkinson’s disease, especially the development of brain pacemakers in the last two decades has provided a new pathway for the treatment of Parkinson’s disease patients. A brain pacemaker is the common name for deep brain electrical stimulation (DBS) therapy, which stimulates the relevant nuclei in the brain that control movement by delivering weak electrical pulses through electrodes implanted in the brain, and has been implanted in more than 150,000 people worldwide. The quality of life of Parkinson’s disease patients has been improved by surgical treatment. Surgical treatment has become a new hope for Parkinson’s disease patients.