The mother and her four children have been diagnosed with thyroid disease over the years. Is it possible that a family’s necks can be “homozygous”? Scientists have found that thyroid disorders do run in families. A few families have mutations in genes such as the autosomal APC, which are signaling proteins involved in the regulation of cell proliferation, and the mutations can lead to abnormal proliferation of thyroid follicles, which are no longer controlled by the body’s “headquarters” and can develop into cancer. The autosomes in a family are part of a “batch of products”, so if one product is “faulty”, the others may have the same “faulty”; it is not surprising that family members have the same thyroid disease one after another. A few days ago, Ms. Wang, 53, found a lump in her neck and had her thyroid gland removed in our department (minimally invasive surgery) at Wuhan First Hospital, the fifth member of her family to suffer from this disease. All four of Ms. Wang’s siblings have had thyroid surgery at the First Hospital for lumps in their necks. Her mother had thyroid disease several years earlier and, like her siblings, all had precancerous thyroid lesions. Therefore, if your family member has thyroid disease, you should also pay attention and go to the hospital as soon as possible if you have neck discomfort or a lump appears. Most of the thyroid diseases can achieve good results as long as they are treated correctly and in time.