Sultanamine, or Cliborol ointment, is different from tacrolimus in terms of pharmacologic effects, scope of application, and adverse reactions. 1. Pharmacological effects: Cliborol ointment can inhibit the increase of intracellular cyclic adenosine monophosphate level; tacrolimus can inhibit T cell activation. 2. Scope of application: Cliborol ointment is mainly used for the treatment of mild to moderate atopic dermatitis; tacrolimus is mainly used for the treatment of moderate to severe atopic dermatitis patients. 3. Adverse reactions: the adverse reaction of Cliborol ointment is atopic dermatitis; the adverse reactions of tacrolimus include headache, sweating, rosacea, seizures and so on. Cliborol ointment and tacrolimus should be used in accordance with medical advice, and is contraindicated in people who are allergic to the drug.