Cholangiocarcinoma is treated through various ways such as surgery, chemotherapy and palliative treatment. 1. Surgery: if patients meet the criteria for surgery, surgery is preferred, and the surgical options include pancreaticoduodenectomy, middle choledochotomy and so on. 2. Chemotherapy: for progressive stage that cannot be surgically resected or accompanied by metastasis, cholangiocarcinoma can be treated with gemcitabine, combined with platinum antitumor drugs such as cisplatin, etc., which can make the tumor go down to a lower stage and get the chance of surgical resection. 3. Palliative treatment: for patients who cannot be cured by surgery, palliative surgery can be performed to alleviate patients’ discomfort and improve patients’ quality of life. Yellowing reduction surgery mainly consists of bile-intestinal anastomosis, which usually can also get better results in improving quality of life. Cholangiocarcinoma patients should go to the hospital in time and choose appropriate treatment under the guidance of doctors.