Prolonged absence of spermatozoa does not usually have a significant effect on sperm quality or adversely affect fertility. The testes produce a large number of sperm every day and will mature after a period of development. Sperm that are not expelled in time will be stored in the epididymis to die slowly and be gradually absorbed by the body, and will not affect the quality of other sperm or affect fertility. To keep sperm fresh, they should be expelled regularly to make room for fresh sperm. Intercourse should be chosen as close as possible to a woman’s ovulation period to help increase the chances of conception. Normally, one should maintain pubic hygiene to avoid pathogen infection; wear loose and breathable underwear to avoid squeezing the testicles; and exercise regularly to enhance physical fitness. If patients have symptoms of abnormal sperm quality, they should go to regular hospitals in time and be treated under the guidance of doctors.