Normal use of tretinoin ointment skin generally do not feel, if the patient with tretinoin ointment after the burning sensation, itching and other manifestations, mostly considered to be due to adverse drug reactions. Trimethoprim ointment is mainly composed of miconazole nitrate, tretinoin acetate, neomycin sulfate, mainly used for the treatment of neurodermatitis, tinea corporis, tinea cruris, tinea cruris, eczema, contact dermatitis, seborrheic dermatitis and other conditions. Generally normal use of Trimethoprim Ointment will not feel. Some patients with tretinoin ointment may appear after the skin burning sensation, itching, pins and needles feeling and other adverse reactions, if the patient long-term use of tretinoin ointment may cause capillary dilatation, skin atrophy, hirsutism, pigmentation abnormalities and other adverse reactions. Generally normal people will not feel with Trimethoprim ointment, it is recommended that those who are allergic to the components of Trimethoprim ointment should disable the drug, and should not use Trimethoprim ointment for a large area for a long time. In addition, patients need to use Trimethoprim ointment under the guidance of the instructions or licensed pharmacists, and cannot use the drug without authorization. If the patient after the use of the drug appeared serious itching or burning sensation, you need to wash the ointment in time, and stop using Trimethoprim ointment.