Comparison of types, uses, advantages and disadvantages of interferons

  The interferon used clinically is mainly divided into: ordinary interferon and long-acting interferon, now from the type, usage, price, efficacy and other aspects of comparison are as follows: ordinary interferon are: 1, interferon alpha-2a, trade name: Rohypnol, Intefen, Belpham; 2, interferon alpha-1b, trade name: Seroquin, Yundein; 3, interferon alpha-2b, trade name: Ganlonen, Andafen, Introne; Usage and dosage: 1 week 3 times or 1 time every other day, intramuscular injection or subcutaneous injection.  Price: 1 injection of several dozen dollars.  Long-acting interferon are: 1, pegylated interferon alpha-2a, trade name: Pyroxin; 2, pegylated interferon alpha-2b, trade name: Pellegrin.  Usage and dosage: 1 time a week, intramuscular injection or subcutaneous injection.  Price: 1 injection is probably between 1000 and 1400 yuan.  The disadvantages of regular interferon are obvious. Due to the fast absorption, the blood concentration reaches its highest after a few hours of injection, when the side effects react strongly and the inhibition of the virus reaches its highest, but due to the relatively fast excretion, resulting in a low blood concentration before the next injection, the virus may resume replication. Long-acting interferon, on the other hand, solves this problem very well, as the blood concentration can be kept constant, and there is no chance of the virus replicating again, and the duration of action is prolonged. Therefore, compared to ordinary interferon, long-acting interferon has the advantage of avoiding frequent injections, and the effect is also better than ordinary interferon, but the price is more expensive, and it is recommended that patients with good financial conditions prefer long-acting interferon.