Do stem cell transplants for hemophagocytic syndrome work?

Hemophagocytic syndromes consist of two types, namely primary hemophagocytic syndrome and secondary hemophagocytic syndrome. The primary treatment for primary phagocytic syndrome i.e. bone marrow hematopoietic stem cell transplantation is effective. Secondary is treated by targeting the cause of the disease. Hemophagocytic syndrome is a serious hematologic disorder that may be life-threatening. Common clinical manifestations include: ① persistent high fever, body temperature often above 38.5℃; ② hepatosplenomegaly; ③ hematopoiesis (including red blood cells, white blood cells and platelets, etc.). 1. Primary hemophagocytic syndrome: the main treatment is bone marrow hematopoietic stem cell transplantation, which is also a more effective treatment. 2. Secondary phagocytic syndrome: it can be secondary to malignant tumors (cancer, etc.), lymphoma, leukocytes, etc. The key to treating secondary phagocytic syndrome lies in the treatment of the primary disease, including surgery, combined chemotherapy, molecular targeting therapy, hematopoietic stem cell transplantation and so on. It is recommended that the patient should immediately visit the Department of Hematology, and develop an individualized treatment plan after completing relevant examinations to carefully evaluate the condition.