Inflammation and pus in the ear piercing is a condition that should not be squeezed by hand. If the ear hole is inflamed and pus is flowing, first of all, you need to disinfect it and remove the contaminants or scabs or crusts from the surface of the pus using the sore-clearing treatment. Then use some medical disinfectant, such as iodophor, to apply topically. If there are infected foci, they need to be removed promptly. At the same time, oral antimicrobial agents are needed for treatment, such as oral roxithromycin, one twice a day, and topical fusidic acid cream or erythromycin cream, three to four times a day.