If Raynaud’s phenomenon is not treated in time, it may cause localized skin changes due to its frequent attacks, or lead to irreversible arterial stenosis, and may also affect vital organs such as the heart, brain, and lungs. 1. Localized skin changes. Since Raynaud’s phenomenon is caused by spasm of the fine arteries at the ends of the limbs due to a variety of reasons. If it is allowed to have frequent attacks, it may lead to nutritional disorders in the skin and nails at the end of the fingers, which may manifest as dry skin, subcutaneous tissue atrophy, ulcers or keratinized indentation of the skin at the root of the nails, slow growth of the nails, nail deformation, and so on. 2. Irreversible arterial stenosis. If the spasm of fine arteries at the end of the limbs occurs for a long time, it may lead to irreversible narrowing of the arteries, resulting in ulcers and gangrene at the ends of the fingers, and even amputation of the limbs is needed for a very small number of people. 3. Affecting vital organs such as the heart, brain and lungs. Raynaud’s phenomenon can sometimes be accompanied by vasospasm of the heart, brain, lungs and other organs, resulting in chest tightness, chest pain, dizziness and other manifestations. It is recommended that people with Raynaud’s phenomenon should consult the rheumatology and immunology department in time and actively treat the disease to prevent it from leading to serious consequences.