Helicobacter pylori, or Hp for short, is a Gram-negative, microaerobic bacterium that lives in all areas of the stomach and duodenum. It causes mild chronic inflammation of the gastric mucosa and may even lead to gastric and duodenal ulcers and gastric cancer. So how should we treat it? At present, the eradication of Helicobacter pylori commonly used in the following programs: 1, proton pump inhibitors (commercially available such as omeprazole, lansoprazole, etc.) + two antibiotics: (1) proton pump inhibitors standard measure + amoxicillin 1.0g + clarithromycin 0.5g, both twice a day, 1 week as a course of treatment; proton pump inhibitors standard measure + amoxicillin 1.0g + metronidazole 0.4g, both twice a day (2) standard measurement of proton pump inhibitor + metronidazole 0.4g clarithromycin 0.25g, both twice a day, 1 week as a course of treatment. 2, bismuth: (1) Lizhu gastric triplet: bismuth (Lizhu Delux) + two antibiotics, is a very effective drug for the eradication of Helicobacter pylori, a course of treatment for seven days, the eradication rate of more than 90%; (2) bismuth + two antibiotics: bismuth (recommended Lizhu Delux) standard dose + amoxicillin 0.5g + metronidazole 0.4g, both twice a day, 2 weeks for a course of treatment (3) standard dose of bismuth (recommended to use Rejuveno) + tetracycline 0.5g + metronidazole 0.4g, both twice a day, 2 weeks as a course; (4) standard dose of bismuth (recommended to use Rejuveno) + clarithromycin 0.25g + metronidazole 0.4g, both twice a day, 2 weeks as a course. 3.Other regimens: (1) Ranitidine bismuth citrate 0.4g replaces the proton pump inhibitor in the recommended regimen 1; (2) Proton pump inhibitor + recommended regimen 2 forms a quadruple therapy for one week. Metronidazole 0.4g can be replaced by tinidazole 0.5g in the regimen.