High lipoprotein A is commonly found in angina pectoris, acute myocardial infarction, cerebral hemorrhage, familial hypercholesterolemia, diabetes mellitus, and so on. The manifestations are different for different diseases, mainly chest pain, chest tightness, dizziness, limb weakness and other symptoms. Lipoprotein A is mainly synthesized in the liver, which can prevent the dissolution of blood clots in blood vessels, and is therefore a risk factor for stroke and coronary heart disease. When it is elevated, it is usually more common in angina pectoris, acute myocardial infarction, and cerebral hemorrhage. Patients with angina pectoris may have sudden severe chest pain and dyspnea. Patients with acute myocardial infarction may have pain in the precordial region as well as a feeling of suffocation. Patients with cerebral hemorrhage may have dizziness, headache, limb weakness, slurred speech, and limb numbness. In addition, elevated lipoprotein A is also seen in familial hypercholesterolemia and diabetes mellitus. Familial hypercholesterolemia will have manifestations such as xanthomas and corneal bowing. Patients with diabetes mellitus usually present with lethargy, polydipsia, polyphagia, and polyuria. In addition to the above factors, elevated lipoprotein A may also be caused by other diseases, and patients are advised to undergo timely treatment.