Gastropathy is a collective term for stomach disorders, and patients with gastropathy do not always have Helicobacter pylori infection. There are various types of gastric diseases, including acute and chronic gastritis, gastric ulcer, gastric polyp, gastric cancer, etc. Helicobacter pylori infection is one of the most important causes of peptic ulcer, gastritis, gastric cancer, etc. However, patients with gastric diseases are not always caused by Helicobacter pylori infection. However, H. pylori infection is not necessarily the cause of all gastric diseases, therefore, H. pylori infection is not necessarily present in all gastric disease patients. In addition to H. pylori infection, other factors can also lead to gastric disease, such as gastric ulcers associated with long-term alcohol consumption, drug stimulation, irregular diet and other factors; gastric polyps may be related to inflammation stimulation, genetic factors. Once diagnosed with gastric disease, it is recommended to consult a doctor in a timely manner, under the guidance of a professional physician to clarify the specific causes of the disease and to carry out targeted treatment.