The causes of chest tightness and vomiting include myocardial infarction and heart failure, as follows: 1. Myocardial infarction: It may be due to coronary artery disease, acute coronary syndrome, and acute myocardial infarction, possibly due to myocardial infarction of inferior wall origin. Patients with myocardial infarction may experience severe chest pain that lasts for a long time, often more than half an hour, and may be accompanied by nausea, vomiting, cold sweats, decreased blood pressure, shock, heart failure, etc. 2. Heart failure: For chest tightness and vomiting may also be heart failure. Patients with heart failure can be caused by various types of organic heart disease, of which coronary heart disease is the most common cause of heart failure. Patients with coronary heart disease may experience chest tightness, chest pain, nausea, vomiting, palpitations, abnormal shortness of breath, etc. The cause of vomiting may be due to gastrointestinal stasis, resulting in abdominal pain, abdominal distention, nausea and vomiting.