Non-infectious glans that is, the cause of the disease has nothing to do with bacteria, viruses and other pathogens, and may be caused by foreskin factors, personal hygiene habits, external stimuli, and other diseases. 1. Circumcision factors. Such as long foreskin, foreskin dysfunction, etc., will stimulate local inflammation. 2. Personal hygiene habits. Such as due to the foreskin is too long or turn over poor reasons, resulting in insufficient local cleaning, long-term past shedding of cells, mucus, urine and other accumulation, can also stimulate the local inflammation; or due to bathing sloppiness, ignoring sexual safety and sexual hygiene leads to inflammation. 3. External stimulation. Such as consuming too stimulating cleaning products leading to excessive cleaning, multiple chemical detergents, trauma, medicines, foreign objects and other stimuli, causing non-infectious glans. 4.Other diseases. Such as diabetes, psoriasis, etc., may also stimulate the occurrence of this disease. It is recommended that people who have the manifestations of redness and swelling of the prepuce and glans mucosa, local itching, tingling, etc., should consult the doctor in time and undergo regular treatment.