Diagnostic indicators of chronic renal failure rely on blood creatinine and endogenous creatinine clearance for diagnosis. Chronic renal failure is a common result of various chronic kidney diseases that continue to progress to the late stage. Chronic renal failure in China can be divided into four stages. Compensated renal function stage (endogenous creatinine clearance Ccr at 50-80ml/min, creatinine Scr133-177μmol/L); Loss of compensation stage (Ccr at 20 to 50 ml/min, Scr186 to 442 μmol/L); Renal failure stage (Ccr 10-20ml/min, Scr451-707μmol/L); Uremic stage (Ccr <10ml/min, Scr4≥707μmol/L). If patients have symptoms such as elevated creatinine, proteinuria, hematuria, edema, etc., it is recommended to go to the hospital in time to improve the relevant examinations under the guidance of the doctor, and actively treat them to avoid the progression of the disease.