In mild cases, although there is no serious harm, patients with urticaria will have more intense itching, which affects the patient’s school work and rest. Patients with more severe urticaria will have significant systemic symptoms, such as fever, coldness and tiredness, and need to rest. The patient’s physical and mental health is greatly affected and cannot work and study. For patients with severe urticaria or with mucosal damage or anaphylaxis, it can be life-threatening. Immediate resuscitation treatment is required. If the respiratory distress or shock is prolonged, it can have serious sequelae on the brain, kidneys and other organs. In the case of chronic urticaria, the rash is mainly aggravated at night, which has a serious impact on the patient’s sleep rest and rest. In turn, it affects the daily work, and long-term lack of sleep can cause dizziness, weakness of the limbs, memory loss and other serious effects on the entire physical and mental health of patients.