Popliteal cyst 10mmx37mm belongs to larger popliteal cysts, which need to be treated, according to the different severity, the treatment modes are also different, there are general treatment, medication, puncture and extraction of fluids and surgical treatment. 1. General treatment: If it is simple popliteal cyst without pain and other symptoms, it can be treated conservatively, with proper rest, elevation of the lower limbs during rest, and avoiding prolonged walking or standing as much as possible. 2. Medication: For patients with localized pain, non-steroidal drugs such as ibuprofen and diclofenac sodium can be chosen to relieve localized pain, and drugs such as cortisone can also be injected into the cyst to reduce inflammation and relieve pain. 3. Puncture and fluid extraction: the fluid inside the cyst can be extracted with a syringe to reduce the pressure of the cyst on the surrounding tissues, but there is a certain possibility of recurrence. 4. Surgery: Including open resection surgery, arthroscopic surgery, etc., the cyst will be directly removed. However, there is still a possibility of recurrence. Popliteal cysts are mostly caused by congenital lesions in the joint cavity, trauma, rheumatoid arthritis and other causes that lead to increased fluid accumulation in the knee joint, causing popliteal cysts. When popliteal cysts are detected, it is recommended to consult a doctor in time for targeted treatment according to the cause of the disease.