Intestinal wall thickening does not necessarily mean cancer. A relatively smooth and even surface with pink color and good elasticity indicates that it may be edema. If it is unevenly thickened and the surface is also not smooth, some of them are accompanied by ulcers and have poor elasticity, cancer is usually considered, but pathology is also needed to confirm the diagnosis. There are many reasons for intestinal wall thickening, most of which are related to people’s living habits. Unhygienic eating habits can lead to the invasion of some bacteria into the human intestinal tract, which leads to various intestinal diseases. Other causes of intestinal wall thickening are immune deficiency lymphoma, hemangioma, etc. There are also chronic schistosomiasis patients and intestinal tuberculosis patients who slowly develop intestinal wall thickening as their condition worsens, but if it is limited, especially stage localized thickening, the possibility of cancer should be considered. However, it should also be differentiated from localized intestinal inflammation. If the thickening of the intestinal wall is found after imaging examination and tumor is suspected or it is suspected to have lesion, first of all, colonoscopy or intensive CT examination should be done to further understand the situation according to the clinical data. Do not worry too much about the thickening of the intestinal wall, when suffering from gastrointestinal diseases must go to the hospital in time for diagnosis and treatment, and reasonable arrangements for their diet.