During hyperthyroidism, the finding of a 6mm thyroid nodule cannot be assessed as serious or not, but requires a comprehensive assessment of the condition in conjunction with clinical symptoms, thyroid hormone levels, thyroid ultrasound, and thyroid tissue biopsy. The size of thyroid nodules is generally not considered to be helpful in predicting or excluding malignant lesions, but the size of the nodule is an important basis for deciding whether or not to perform a puncture biopsy of the nodule, and is also an important assessment indicator during the follow-up process. Patients with hyperthyroidism combined with thyroid nodules can be evaluated comprehensively by clinical symptoms, thyroid hormone levels, thyroid ultrasound, and thyroid tissue biopsy. Patients with hyperthyroidism should be actively treated for the primary disease, including medication, radioactive iodine, and surgery. For thyroid nodules, if the likelihood of the nodules being benign is high as assessed by thyroid ultrasound, there is no need for special treatment for the nodules, and the patient should undergo regular review to observe whether there are any changes in the nodules. If the nodules are malignant, surgical treatment is required. It is recommended that the patient seek medical attention and treatment in a timely manner.