Chronic inflammation of gastric sinus mucosa with glandular hyperplasia can be treated with general treatment, medication and surgery. 1. General treatment: patients must adjust their diet, avoid spicy and stimulating food and too cold and too hot food, try to eat a light and easy to digest, and avoid overeating. 2. Drug therapy: often need to take drugs to inhibit gastric acid secretion, such as omeprazole, rabeprazole, due to the existence of certain gastric mucosal damage can be combined with gastric mucosal protective agents, such as aluminum sulfate, colloidal bismuth pectin. 3. Surgical treatment: If there is gastric space-occupying lesions, such as adenomatous polyps, they need to be surgically removed endoscopically as early as possible. Chronic inflammation of gastric sinus mucosa with adenomatous hyperplasia, need to cooperate with the doctor for examination and treatment, to avoid delay in treatment.