Spring infectious diseases can be prevented by wearing masks, gathering less, washing hands frequently, strengthening physical exercise, going to bed early and getting up early, and having a regular routine. Spring infectious diseases include measles, rubella, chickenpox, hand-foot-mouth disease, mumps, scarlet fever, etc. These infectious diseases are mainly spread through respiratory droplet transmission, close contact transmission, etc. Therefore, attention should be paid to cutting off the transmission pathway for prevention, which can be prevented by wearing masks and going to fewer gathering places to participate in congregational activities. In addition, due to the use of contaminated living utensils, tableware, etc. can also cause the spread of spring infectious diseases, so we should pay attention to food hygiene, hand washing. Strengthening physical exercise, regular work and rest, going to bed early and waking up early to ensure sufficient sleep can enhance personal immunity, which is also important for the prevention of spring infectious diseases.