Current research shows that the new crown vaccine has almost no effect on human skin, after vaccination, the inoculation point may appear transient redness, swelling, hard nodules, high safety can be assured that the vaccination. New crown vaccination may have some effects on the body, resulting in some reversible adverse reactions such as redness, swelling and hard nodules at the point of inoculation, headache, dizziness, mental fatigue, joint and muscle pain, etc., but the symptoms are relatively mild and can be relieved by themselves within 3 days or so. Most people do not have any clinical reaction after receiving the new crown vaccine, which is related to the individual’s physical condition and the type of the new crown vaccine. Usually, the adverse reactions after receiving the adenovirus vector vaccine are greater than those of the inactivated vaccine. Regardless of the type of NeoCrown vaccine, it has little or no effect on the skin and is safe for those who are eligible to receive it.