Pancreatic insufficiency can be manifested as symptoms of exocrine, i.e. digestive, and endocrine, i.e. dysfunction of blood glucose regulation. 1. Symptoms caused by pancreatic exocrine dysfunction include dyspepsia, diarrhea, constipation, abdominal distension, malnutrition and other symptoms. Insufficient pancreatic function leads to insufficient secretion of pancreatic amylase, pancreatic protease, pancreatic lipase and chymotrypsin, which leads to insufficient digestion and absorption of sugar, fat and protein, thus causing clinical symptoms such as digestive discomfort and malnutrition. 2. Pancreatic endocrine dysfunction can lead to diabetes mellitus due to insufficient insulin secretion. The endocrine function of the pancreas is to secrete insulin to regulate blood glucose. Pancreatic dysfunction can lead to insufficient insulin secretion, poor hypoglycemic function, and elevated blood glucose level, thus leading to diabetes. If you suspect pancreatic insufficiency, you need to go to the hospital in time to get a clear diagnosis and treatment plan, and use medication under the doctor’s guidance to avoid self-medication.