The hardening of the stratum corneum on the bottom of the foot is considered a high possibility of keratosis pilaris. It is recommended to pay attention to moisturizing in general and avoid excessive washing. You can give topical application such as vitamin A acid cream and urea cream topically to promote skin softening. At the same time, it can be combined with a mild and non-stimulating moisturizing cream. It is best to soak the feet in warm water before using the medication to soften the skin and then give the medication, the effect will be better. For serious cases, you can go to a regular hospital to improve liver function tests and blood lipid tests, and then give oral vitamin A acid. Avoid drinking alcohol during the medication period, need to regularly check liver function and blood lipids, and must use the medication under the guidance of a doctor, not on your own to avoid adverse reactions.