Whether or not depression can be cured by taking medication is determined by the severity of the depression. In case of mild and moderate depression, it is possible to be cured by taking medication, while for severe depression, medication may only play a role in relieving the problem and cannot cure it completely. Patients with mild depression are potentially curable and can be treated with medications such as fluvoxamine, sertraline, and bupropion under the direction of a doctor. At the same time through the drug treatment, it is recommended to cooperate with the psychotherapy at the same time, in order to help relieve and treat the symptoms of depression. For patients with severe depression, medication can be used as the basis, such as the use of paroxetine, fluoxetine, escitalopram and other drugs for systematic and standardized treatment, but also professional psychotherapy and self-adjustment and other ways, in addition to modified electroconvulsive therapy, repetitive transcranial magnetic stimulation and other ways to alleviate the patient’s depressive symptoms. Depression is a disease that is easy to relapse. Patients should pay attention to adjusting their mood in daily life while cooperating with the doctor’s treatment, communicate with family members and friends, relax through appropriate physical exercise, ensure sufficient rest, and avoid exertion.