Severe cardiac reflux may lead to heart failure, induced arrhythmias and circulatory stasis. 1. Heart failure: the heart can compensate for the increase in stroke volume and ejection fraction in the early stage of cardiac regurgitation, but with the gradual development of the disease, it will show the manifestation of left heart failure in the stage of decompensation. 2. Induce a variety of arrhythmias: If the heart regurgitation for the left ventricle mitral valve regurgitation, mainly caused by the left atrium enlargement, so that the left atrial pressure increases, easy to induce a variety of arrhythmias, including atrial flutter, atrial tachycardia, atrial fibrillation. And the aortic valve regurgitation, will regurgitate to the left ventricle, there will be dilatation and hypertrophy of the left ventricle. 3. Circulatory stasis: cardiac regurgitation may also cause circulatory stasis, which may be manifested as edema, pleural effusion, abdominal effusion, hypotension, gastrointestinal stasis, and hepatic stasis, etc. If the diagnosis of cardiac regurgitation is confirmed, it may lead to atrial flutter, atrial tachycardia, and atrial fibrillation. If cardiac reflux disease is diagnosed, it is recommended that standardized treatment be carried out as soon as possible and as prescribed by the doctor in order to reduce the adverse effects of the disease.