If women of advanced age want to have children, they should go to a specialized fertility hospital for consultation, checking ovarian function and obtaining blastocysts through specialized assisted reproduction techniques. Currently, in-vitro culture of blastocysts is an option for women with advanced infertility, which uses specialized techniques to screen high-quality blastocysts and then transfer them to the mother. Blastocyst culture refers to the in vitro culture of embryos to the 3rd day of cleavage stage, and continue to culture to the 5th-6th day to become blastocysts. Blastocyst transfer increases the rate of embryo implantation and decreases the rate of pregnancy loss. Blastocyst culture is suitable for women who have failed multiple transfers and are partially advanced in age but have good ovarian function, and need to ensure a sufficient number of eggs and an objective number of embryos. The biggest advantage of blastocyst culture is that it has a high IVF pregnancy rate and is less likely to fail after transfer. It is recommended that senior women who have the need to prepare for pregnancy go to a professional reproductive hospital for consultation.