Metformin tablets and metformin extended-release tablets are glucose-lowering drugs of the same composition, there is no difference in efficacy, mainly in the different time of drug metabolism in the body, metformin extended-release tablets in the body to extend the release time compared with metformin tablets. Metformin tablets and metformin extended-release tablets are both glucose-lowering drugs, metformin tablets compared with metformin extended-release tablets can prolong the release and absorption of the drug in the body, so as to achieve the purpose of prolonging the duration of drug action. With the increased dosing interval, patients are able to use the medication more conveniently. Adverse reactions such as diarrhea, nausea, and vomiting may occur when using Metformin Tablets or Metformin Extended-Release Tablets. The drug is contraindicated in patients suffering from kidney disease, allergy to drug components, and kidney function should be monitored regularly during the use of the drug. Note that the drug should be used under the guidance of a doctor, avoid unauthorized use of the drug to avoid adverse effects. If persistent discomfort occurs during the use of the drug, it is recommended to consult a doctor in time and take appropriate measures to deal with the situation.