Drinking milk during puberty may increase the likelihood of acne. Milk contains casein and whey proteins, and casein is able to activate insulin-like growth factor (IGF-1), which promotes the production of sebum by the sebaceous glands of the skin, ultimately leading to the development of acne. Whey protein can stimulate insulin secretion, activate a certain protein kinase, aggravate insulin resistance and induce or aggravate acne. In addition to this, milk contains other steroidal reproductive hormones that may aggravate acne. Drinking milk may induce or aggravate acne, acne people should pay attention to the appropriate adjustment of the diet structure, balanced nutrition, eat less spicy and stimulating food, develop good sleep habits, try to avoid staying up all night.