Nicorandil is effective for 8 hours and this product can be used for angina pectoris and should be used as directed by a physician. Nicorandil is commonly available in tablet form, and the instructions state that the maximum blood concentration is reached after 2 hours of administration, but disappears almost completely after 8 hours. Therefore, it is effective for about 8 hours. Nicorandil dilates coronary blood vessels, increases coronary blood flow, relieves coronary vasospasm, and can be used to treat angina pectoris. Nicorandil adverse reactions include liver dysfunction, thrombocytopenia, mouth ulcers, anal ulcers, tongue ulcers, peptic tube ulcers, headache, stomatitis, and thrombocytopenia. The drug is contraindicated for those who are allergic to the product or niacin, taking vardenafil hydrochloride hydrate, sildenafil citrate, tadalafil. The drug should be used rationally under the guidance of a doctor.