Pepper-like burning sensation on the hands, may be related to contact dermatitis, may also be related to peripheral neuritis and burns and other factors, treatment, respectively, need to be given to the symptomatic anti-allergic, nutritive nerves, as well as analgesic drug therapy. 1. Allergic dermatitis caused by burning sensation of the skin, and skin contact with irritating substances, in the treatment of the first is to keep the skin clean, and then give some anti-allergy drugs, such as fluoro easy, dexamethasone cream, and so on. 2. Burning sensation caused by peripheral neuritis is related to local nerve damage and abnormal sensation, which is mainly treated with nerve-nourishing drugs, such as vitamin B1 and methylcobalamin. 3. Burning sensation caused by burns, in the treatment of the main choice of ice and oral pain medication, such as nimesulide dispersible tablets and so on. Due to the different causes, the treatment is different, the specific situation must first ask the doctor for an interview.